Colon Cancer of a Bangladeshi 17-Year-Old Girl without Known Genetic Predisposition Following Enteric Fever Induced Complication.
Published on September 18, 2025
01 Research Methods
Generally, young-onset CRC is the “hallmark” of hereditary CRCs with highly penetrant germline mutations. However, the bulk of young-onset CRCs appear to be sporadic and therefore the molecular mechanisms driving cancer initiation and progression are unclear.
02 Key Results
Young patients present with more advanced-stage disease at diagnosis compared with older patients. The diagnosis of CRC in young patients is usually delayed because it's seldom suspected. Acute bowel symptoms necessitate immediate exploration at which era perforation of the massive bowel with multiple metastatic deposits may be observed. Ileus by tumor occurs more frequently in adolescents than in adults with this cancer.
03 Conclusion
A 17-year-old female patient with abdominal pain perforation and colon obstruction thanks to sporadic carcinoma with mucinous histology.